In the 11th century, Lomello became the residence of the Palatine Counts to whom the reconstruction of the previous Lombard castle can be traced, which is next to the Basilica of Santa Maria Maggiore and was destroyed in 1155.

In 1450 the Castle was reconstructed by Antonio Crivelli (invested by the lordship over that land of Francesco Sforza), which together with his successors, gave it its current appearance. It is currently used as the town hall for Lomello. The castle comprises the avant-corps in the form of a tower which is accessed via a stone bridge, and a second tower which looks more like a manor house than an actual fortress.